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Available for Android and iOS devices. It is best to read this information with our general information about the type of cancer you have.. Interferon is a type of immunotherapy drug called an immune system modulator. Adults. Relapse of drug addiction has also happened. Interferon alfa has shown some antitumour effect in certain lymphomas and solid tumours. Description of Clinical Studies PMID: 7993128 Abstract There are three types of interferons (IFN), alpha, beta and gamma. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Some drugs may have another patient information leaflet. IFNs belong to the large class of proteins known as cytokines, molecules used for communication between cells to trigger the protective defenses of the immune system that help eradicate pathogens. Alpha-interferon was recently approved in Canada for the treatment of chronic hbv or hcv hepatitis and is the only approved therapeutic agent. Hypersensitivity to human interferon alpha proteins, mouse IgG, egg proteins, or neomycin. Do not flush down a toilet or pour down a drain unless you are told to do so. If you have questions about side effects, call your doctor. Generic Name : Interferon Alfa 2A Pronunciation : IN-ter-FEER-on ALfa Latest prescription information about Interferon Alfa 2A. Generic Name: Interferon Alfa-n3 (in ter FEER on AL fa en three)Brand Name: Alferon N. Medically reviewed by Drugs.com. 4. strokes have happened. help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. any drug without checking with your doctor. Interferon alpha is currently recommended as an option for first-line therapy for individuals with essential thrombocythaemia or polycythaemia vera in whom cytoreduction is indicated. autoimmune diseases worse. taken, how much, and when it happened. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Malignant melanoma. You may also report side effects at https://www.fda.gov/medwatch. Use. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. breath that smells like fruit. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Interferon alpha is currently recommended as an option for first-line therapy for individuals with essential thrombocythaemia or polycythaemia vera in whom cytoreduction is indicated. Interferon alfa-2a acts similarly to native interferon alpha. It was developed at Biogen, and ultimately marketed by Schering-Plough under the trade name Intron-A. Not hungry. Interferon alfa-2a dosage information (in more detail). increased thirst tiredness urinating more often than normal increased appetite weight loss your breath smells like fruit You will need to talk about the benefits and risks of using interferon alfa-n3 Interferon alfa-n3 dosage information (in more detail). Interferon alfa-2b is an antiviral or antineoplastic drug. There may be drug take-back programs in your area. The major subtypes identified are IFN-α1, IFN-α2, IFN-α8, IFN-α10, IFN-α14 and IFN-α21. Check with your pharmacist. The nebulized interferon alfa-2b formulation is not approved by the Food and Drug Administration for use in the United States. Infection, neutropenia. Not able to sleep. Medically reviewed by Drugs.com. Peginterferon alfa, interferon alfa, and ribavirin for moderate to severe chronic hepatitis C (January 2004 and September 2010) NICE TA200. For melanoma it is used in addition to surgery. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. AIDS-related Kaposi's sarcoma 2. INTRON ® A (Interferon alfa-2b) for intramuscular, subcutaneous, intralesional, or intravenous Injection is a purified sterile recombinant interferon product.. Intron A recombinant for Injection has been classified as an alpha interferon and is a water-soluble protein with a molecular weight of 19,271 daltons produced by recombinant DNA techniques. Hypersensitivity to human interferon alpha proteins, mouse IgG, egg proteins, or neomycin. This medicine may raise blood sugar. In a typical scenario, a virus-infected cell will release interferons causing nearby cells to heighten their anti-viral defenses. Suicide or suicidal thoughts, thoughts of hurting others, depression, forceful actions, hallucinations, and other mood or behavior problems have happened during treatment and within 6 … Fatigue (8-96%) Fever (34-94%) Neutropenia (92%) Flu-like syndrome (79%) Myalgia (28-75%) Anorexia (1-69%) Leukopenia (68%) Nausea (17-66%) Transaminases increased (13-63%) Weakness (63%) Headache (21-62%) Chills (54%) Diarrhea (2-45%) Rigors (42%) Depression (up to 40% of pts), suicidal ideation/ attempts, suicide Alopecia (38%) Dyspnea (34%) Somnolence (33%) Vomiting (2-32%) Anemia (32%) Cough (31%) Pharyngitis (31%) Chest pain (28%) Xerostomia (28%) Rash (25%) Dizziness (24%) Taste al… to make sure that it is safe for you to take interferon alfa-2a with all of your drugs and health problems. Some drugs may have another patient information leaflet. Interferon alpha is the generic name for the trade name drugs Intron® A, Roferon®-A. Closely read the part in this leaflet which lists when to call your doctor. It inhibits replication of a wide range of RNA and DNA viruses. what signs you had. Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or prednisone, methotrexate, dexamethasone, Keytruda, Imbruvica, hydroxyurea, cyclophosphamide, Revlimid, Avastin, pembrolizumab. Tell your doctor There are many drugs that can do this. What are some other side effects of Interferon Alfa-2a? Interferon gamma upregulates TNF-alpha, interferon-beta, and IL-1, which enhance macrophage activity, while downregulating the production of macrophage inhibitory cytokines IL-4 and IL-10. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Low white blood cell counts have rarely happened with interferon alfa-n3. If you have any of these health problems: Kidney disease or. Cautions. Information about drug Interferon Alpha-2B includes cost of the drug and the type of drug - tablet, capsule, syrup, cream, gel, ointment, liquid or injection. Interferon alfa-2b is also sometimes used to treat hepatitis D virus (HDV; swelling of the liver caused by a virus), basal cell carcinoma (a type of skin cancer), cutaneous T-cell lymphomas (CTCL, a type of skin cancer), and kidney cancer. This may lead to a higher chance of getting an infection. If you think you have any of these health problems, call your doctor right away. This includes your doctors, nurses, pharmacists, and dentists. Tell your doctor if you are breast-feeding. disease in which body has immune response against itself. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not give to a child younger than 3 years of age. You must check Endogenous alpha-interferons (IFNs) are secreted by leukocytes (e.g., macrophages, B lymphocytes, and non-B non-T lymphocytes) in response to viral infection or various synthetic and biological inducers. Signs of an allergic reaction, like rash; Signs of infection like fever, chills, very bad. If you have questions about side effects, call your doctor. Tell your Roferon-A (interferon alfa-2a, recombinant) is indicated for the treatment of chronic hepatitis C and hairy cell leukemia in patients 18 years of age or older. Generic Name: Interferon Alfa-2a (in ter FEER on AL fa too aye). Keep all drugs out of the reach of children and pets. It is given as a shot into the fatty part of the skin. Interferon alfa-2b is also sometimes used to treat hepatitis D virus (HDV; swelling of the liver caused by a virus), basal cell carcinoma (a type of skin cancer), cutaneous T-cell lymphomas (CTCL, a type of skin cancer), and kidney cancer. The individual interferon alpha proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156 - 172 amino acids (aa). Check with your Do not give into skin that is irritated, bruised, red, infected, or scarred. [Article in Japanese] Author J Imanishi 1 Affiliation 1 Dept. This medication is used to treat various cancers (e.g., leukemia, melanoma, AIDS-related Kaposi's sarcoma). Patients should be monitored closely with periodic clinical and laboratory evaluations. 4 Interferon alfa-2b, 5 recombinant 6 For Injection 7 8 WARNING 9 Alpha interferons, including INTRON® A, cause or aggravate fatal or life-threatening 10 neuropsychiatric, autoimmune, ischemic, and infectious disorders. Do not use if the solution is cloudy, leaking, or has particles. the last dose. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Sayiner ZA, Eraydın A, Metin T, Özkaya M. Interferon alpha-induced non-immune thyrotoxicosis treated by plasmapheresis. Interferon alfa-2b is a prescription medication used to treat chronic hepatitis B, chronic hepatitis C, certain type of genital warts, hairy cell leukemia, malignant melanoma, AIDS-related Kaposi's sarcoma, and follicular lymphoma.. Interferon alfa-2b belongs to a group of drugs called interferons. You will need to talk about any risks to your baby. These interferons have been classified into two types: type I includes the alpha and beta forms, and type II consists of the gamma form. Two types of interferon are FDA-approved as adjuvant treatment for patients with high-risk melanoma: Interferon alfa-2b (Intron A) and peginterferon alfa-2b (Sylatron). PRODUCT INFORMATION INTRON A Interferon alfa-2b, For Injection A, cause or aggravate fatal or life-threatening neuropsychiatric, autoimmune, ischemic, and infectious disorders. Do not share needles or other things like toothbrushes or razors. Interferon-alpha has been used as both systemic and intracavitary therapy for primary craniopharyngiomas. Ask your doctor or pharmacist if you Condyloma Acuminatum 3. Diarrhea . pharmacist if you have questions about the best way to throw out drugs. Available for Android and iOS devices. This medicine may be used with other drugs to treat your health condition. Tell all of your health care providers that you take interferon alfa-n3. Call your doctor right away if you have signs of infection like fever, chills, or … If you need to store interferon alfa-n3 at home, talk with your doctor, nurse, or pharmacist about how to store it. Talk with a doctor or pharmacist if you have any questions. Do not use the same syringe more than one time. Signs of liver problems like dark urine, feeling tired, not hungry. Suicide or suicidal thoughts, thoughts of hurting others, If your symptoms or health problems do not get better or if they become worse, call your doctor. doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. Tell your doctor if you are pregnant or plan on getting pregnant. Indications and dose. By subcutaneous injection. high amount of triglyceride in the blood. If you are allergic to interferon alfa-2a; any part of interferon alfa-2a; or any other drugs, foods, or substances. Use a soft toothbrush and an electric razor. Three forms of interferon— alpha (α), beta (β), and gamma (γ)—have been recognized. You may report side effects to the FDA at 1-800-332-1088. 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